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Lab Operations Associate

BigHat Biosciences

BigHat Biosciences

Operations
San Mateo, CA, USA
Posted on Mar 13, 2026
The Role: BigHat Biosciences is seeking a self-motivated individual to support the expansion of lab operations functions and to support broader platform growth. This role will enable the development of existing and new capabilities within Lab Operations, take ownership of growing functional areas, and help to support the expansion of lab operations at BigHat. This role reports directly to the Lab Manager.
Department
Lab Science
Employment Type
Full Time
Location
San Mateo, CA
Workplace type
Onsite
Reporting To
Tasha Mathews

This role's hiring manager:
Tasha Mathews

Key Responsibilities

  • Inventory incoming and existing materials, track quantities and order more as needed, and restock shelves with necessary materials.
  • Respond to purchasing requests from lab users, routing through the appropriate level approval pathways and placing orders for requested items.
  • Take leadership of vendor relationships and coordination of support and maintenance services.
  • Coordinate, perform, troubleshoot, and document laboratory instrumentation events, communicating updates to the broader team.
  • Ensure all projects have the materials and instrumentation necessary to run smoothly.
  • Obtain certification for handling, shipping, and disposal of hazardous materials and coordinate shipments and pickups as needed, maintaining good documentation of events.
  • Maintain the cleanliness, safety, and organization of the lab and storage spaces.
  • Assist with and own documentation of various related areas such as SDS management, SOP writing and processing, and hazardous waste documentation.
  • Communicate with lab team members to understand, respond to, and communicate their needs.

Skills Knowledge and Expertise

  • BS in Biology, Chemistry, or a related field, with 1+ year(s) of industry experience.
  • Experience in a laboratory environment, with experience in lab operations, inventory management, documentation systems, purchasing systems, or instrumentation maintenance a plus.
  • Self-motivated individual with attention to detail, excited to work in a dynamic start-up environment.
  • Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
  • Excellent record-keeping abilities.
  • Experience with Google Suite, with a focus on Google Sheets.
  • Experience with LIMS, lab management, and organizational software is a plus.

Total Rewards

The salary estimated for this position is $80,000 - $105,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave

About BigHat Biosciences

BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology.

BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.
BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC.

Our Hiring Process

Stage 1:

Applied

Stage 2:

Initial Conversation | Head of Talent

Stage 3:

Initial Conversation | Hiring Manager

Stage 4:

1st Technical Screen

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