Senior Software Engineer II

Freenome

Freenome

Software Engineering

Brisbane, CA, USA

Posted on May 5, 2026

About this opportunity:

At Freenome, we are seeking a Senior Software Engineer II to join our innovative Engineering team. The ideal candidate is an experienced backend engineer with a strong background in developing scalable and reliable software solutions. You will play a crucial role in designing, building, and maintaining backend services that support our mission to detect cancer early. This position requires a collaborative mindset, as you will work closely with an interdisciplinary team of engineers, scientists, and product managers to deliver high-quality software solutions. You are passionate about software development best practices and will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer.

The role reports to our engineering management team. This role will be a Remote role.

What you’ll do:

  • Design, develop, and deploy reliable, maintainable, scalable, and fault-tolerant backend services that power both our internal and external systems.
  • Collaborate with interdisciplinary teams, including scientists, product managers, and other engineers, to solve complex problems and deliver high-quality software solutions.
  • Mentor and guide junior engineers, fostering their growth and enhancing the team's technical expertise.
  • Lead code and design reviews, champion engineering best practices and promote a culture of quality and collaboration.
  • Contribute to the development of data infrastructure for machine learning applications, ensuring efficient data processing and integration.
  • Drive the implementation of engineering hygiene practices, ensuring the reliability and maintainability of our systems.
  • Advocate for and implement innovative software development methodologies and tools to improve team efficiency and product quality.

Must haves:

  • Bachelor of Science in Computer Science, Engineering, or related field or equivalent training, fellowship, and/or work experience.
  • At least 8 years of experience as part of a software development team successfully shipping software products, including leading projects from end-to-end and mentoring others.
  • Proficiency in Python and experience with backend development in a team production environment.
  • Strong experience with containerization and orchestration technologies such as Docker and Kubernetes.
  • Familiarity with cloud platforms like AWS, Azure, or Google Cloud Platform.
  • Proven experience in designing and implementing scalable backend systems, with a focus on reliability and performance.
  • Excellent written and verbal communication skills, with a mindful and transparent approach to collaboration.

Nice to haves:

  • Understanding of statistical and machine learning methods, with practical experience in applying them to real-world problems.
  • Expertise in developing ETL or data pipelines that run at scale, utilizing common workflow management systems like Flyte, Airflow, or similar.
  • Domain-specific experience in computational biology, genomics, bioinformatics, or a related field.
  • Experience working in an FDA regulated environment, with a strong understanding of compliance requirements and best practices.

Benefits and additional information:

The US target range of our base salary for new hires is $161,925 - $227,325. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

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