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Innovation Endeavors

Scientist Sr/Pr - Structural Biology

Think Bioscience

Think Bioscience

Marketing & Communications
Boulder, CO, USA
Posted on Wednesday, May 31, 2023

Think Bioscience

Sr/Pr Scientist: Structural Biology and Protein Sciences

Boulder, ColoradoFull-time
About the Job
Senior/Principal Scientist, Structural Biology and Protein Sciences

Company Description:
Think Bioscience is reimagining synthetic biology by using living systems to guide the design and assembly of better medicines. Our unique platform combines applied microbiology, enzymology, and data science to develop small-molecule therapeutics against elusive targets.

We are passionate about improving the lives of patients with innovative science. Our success relies on an exceptional team. If you share our passion, let’s work together. 

Job Description:
  • We are seeking a highly motivated structural biologist with experience in protein biochemistry and biophysics to oversee our structural biology pipeline to enable the discovery of novel small molecule therapeutics.
  • You will join a dynamic team of scientists and assume a leadership role in advancing small molecule drug discovery programs to the clinic.
  • Provide structural biology support to therapeutic development programs via internal and external workflows leveraging crystallography, cryo EM, or NMR as needed.
  • Collaborate with our internal and external biochemistry teams to produce recombinant protein and to carry out biophysical characterization of proteins and protein-ligand complexes (e.g., SPR, DSF, NMR, calorimetry).
  • Work closely with the company’s SAB and other key stakeholders to advance our pipeline programs. 
  • Author or contribute to abstracts/manuscripts, patents, study reports, and regulatory submissions.
  • Ph.D. with at least 3 years of structural biology experience or a B.S. or M.S. and at least 10 years of experience.
  • Successful track record of driving drug discovery programs forward by providing structural biology support.
  • Deep understanding of the structure/function and enzymology of phosphatases and kinases
  • Experience leading and coordinating research teams (external academic, CRO, internal) working concurrently on multiple projects.
  • Adaptability and flexibility to work in a dynamic startup environment.
What We Offer: 
  • A collaborative environment for innovative science and a mission-driven company.
  • Opportunity to lead a critical function in a fast-growing startup and contribute directly to company success.
  • Highly competitive compensation and benefits package, including a salary range of $95,000 - $160,000 per year (title and salary commensurate with experience) and stock options for a fast-growing startup company.
Think Bioscience is an equal opportunity employer and committed to a diverse workplace. All applicants will be considered equally without regard to race, color, ethnicity, veteran status, religion, national origin, marital status, political affiliation, age, sex, sexual orientation, disability status, membership in an organization or any other non-merit factors.